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Information × Registration Number 0218U002059, 0112U000096 , R & D reports Title Features of the structure of the immune and endocrine systems in immunostimulation and immunosuppression. popup.stage_title Head Komarevtseva Irina Olexandrivna, Registration Date 10-01-2018 Organization Lugansk state medikal uneversity popup.description2 The work is devoted to the study of the relationship of bone marrow morphogenesis with the organs of the immune system at various stages of ontogenesis at different states of the immune status. As a result of the study, it was found that the degree of severity of reactivity from the bone system depends on the morphological state of the thymus, spleen, axillary lymph nodes, on the immune status and age of the organism. The use of thymectomy and cyclophosphamide, which cause immunosuppression, leads to a change in the ultrastructure of hydroxyapatite crystals, which negatively affects the processes of mineralization, leads to a decrease in the strength of bones and inhibits the rate of their growth. Product Description popup.authors Вишницька Ірина Анатоліївна Кравцова Юлія Вікторовна popup.nrat_date 2020-04-02 Close