Search academic texts

Information × Registration Number 0218U002061, 0118U001023 , R & D reports Title Molecular-biochemical mechanisms of migration of transplanted stem cells into the hypoxia zone on a model of ischemia / reperfusion syndrome. popup.stage_title Head KomarevtsevVitaliy Mikolaevich, Registration Date 10-01-2018 Organization Lugansk state medikal uneversity popup.description2 The work is devoted to the study of biochemical processes of renal tissue repair after acute renal failure with the introduction of allogeneic mesenchymal stem cells in assessing the state of energy metabolism, the dynamics of the activity of antioxidant defense enzymes, the parameters of nuclear magnetic resonance relaxation, the dynamics of apoptosis processes and the functional state of the kidneys. In the cortical and medullary substance of the renal tissue, the level of energy metabolism was determined by the content of adenyl nucleotides, the level of antioxidant protection of the tissue by the activity of superoxide dismutase, catalase; level of nitrite anion content; the level of apoptosis by DNA fragmentation and the content of free sphingosine. Product Description popup.authors Вишницька Ірина Анатоліївна Кравцова Юлія Вікторовна popup.nrat_date 2020-04-02 Close