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Information × Registration Number 0218U002069, 0116U000184 , R & D reports Title To develop a treatment regimens for patients with pulmonary sarcoidosis with resistance to corticosteroid therapy or contraindications for corticosteroids use popup.stage_title Head Gavrysiuk Volodymyr, Registration Date 12-01-2018 Organization Institute of tuberculosis and pulmonology named by F. G. Yanovsky popup.description2 Object - 24 patients with respiratory sarcoidosis with resistance to corticosteroids or contraindications to corticosteroids use. Aim - to increase the effectiveness of treatment in patients with pulmonary sarcoidosis with resistance to corticosteroids or contraindications to corticosteroids use. Methods - clinical, chest computed tomography, spirometry. It was established that azathioprin was not effective in patients with pulmonary sarcoidosis. Unlike azathioprin and leflunomide, methotrexate was more effective with additional advantage in terms of better tolerability profile. There was developed a "Method of therapy of patients with pulmonary sarcoidosis with resistance to corticosteroids or contraindications to corticosteroids". This method reduces the rate of relapses and has less liver toxicity. Sphere of application - pulmonology, phthisiology. Product Description popup.authors Беренда Олена Анатоліївна Гаврисюк Володимир Костянтинович Гуменюк Галина Львівна Дзюблик Ярослав Олександрович Заворотня Неоніла Павлівна Лещенко Сергій Іванович Меренкова Євгенія Олександрівна Морська Наталія Дмитрівна Пендальчук Наталя Володимирівна Ячник Анатолій Іванович popup.nrat_date 2020-04-02 Close