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Information × Registration Number 0218U002072, 0113U000187 , R & D reports Title To study the local immunomorphological reactions of lung tissue in patients with chronic tuberculous process popup.stage_title Head Liskina Irina Valentinovna, Registration Date 12-01-2018 Organization Institute of tuberculosis and pulmonology named by F. G. Yanovsky popup.description2 Object - 102 histological samples of tissue with pulmonary tuberculomas and 36 samples of biopsies obtained at FBS. Methods - histologic, immunohistochemical, statistical. Aim - to determine immunomorphological signs of local cells reactions that are characteristic of specific chronic tuberculous inflammation in human lung tissue. The advantages and disadvantages for detection of MBT and their antigens by Ziehl-Neelsen, fluorescence and immunohistochemical methods were established. It was determined the feasibility of their use, including - complex from theoretical and practical positions. The diagnostic efficacy was: the Ziehl-Neelsen method 91.2%, the fluorescent - 94.1% and the immunohistochemical study - 97.1%. The "Method of morphological diagnosis of tuberculous infection" was developed, its diagnostic expediency was determined, in particular, for biopsies with fibrobronchoscopy. The efficiency of the method is 77.8%. Sphere of application - phthisiology, pathomorphology Product Description popup.authors Загаба Людмила Михайлівна Кузовкова Світлана Дмитрівна Ліскіна Ірина Валентинівна Мельник Ольга Олександрівна Овчаренко Олена Віталіївна Рекалова Олена Михайлівна popup.nrat_date 2020-04-02 Close