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Information × Registration Number 0218U002502, 0113U002509 , R & D reports Title Development of electrochemical mono- and multisensors for determination jd main blood metabolites: metrological and experimental work. Development of mono- and multisensors elements. Metrology and standartization of biosensors, experimental work popup.stage_title Head Soldatkin Alexei, Доктор біологічних наук Registration Date 29-03-2018 Organization Institute of molecular biology & genetics popup.description2 A multibiosensor based on pH-sensitive field transistors and immobilized enzymes (glucose oxidase, urease and creatinine deiminase) has been developed for the simultaneous determination of human basic metabolites such as glucose, urea and creatinine in biological fluids. The laboratory prototype of the multibiosensor has been created, which demonstrated a high selectivity with respect to its substrates and possible interferences. In real conditions close to the conditions of the clinic, the concentrations of the above-mentioned metabolites in serum and dialysis of blood of patients with renal failure were simultaneously determined and a high level of correlation with traditional methods of analysis was demonstrated. In addition, monobiosensor elements for the determination of uric acid and arginine have been developed, and laboratory samples have been developed that have been tested in real-world assays. Product Description popup.authors Єльська Г.В. Архипова В.М. Білоіван О.А. Дзядевич С.В. Зінченко О.А. Калініченко Л.А. Корпан Я.І. Костюченко Н.І. Кукла О.Л. Кучеренко І.С. Марченко С.В. Пєшкова В.М. Пушкарьов В.М. Рачков О.Е. Сергеєва Т.А. Солдаткін О.О. Чабанова М.В. Шкотова Л.В. popup.nrat_date 2020-04-02 Close