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Information × Registration Number 0218U003119, 0115U003683 , R & D reports Title Development of nanobiomedical technology for recording of cell electrical activity by means of quantal dots. popup.stage_title Head Bilan Pavlo Volodymyrovych, Registration Date 19-01-2018 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 This research proposes a new method for recording the electrical network activity of excitable cells of an organism using semiconductor quantum dots (QD). At the third stage of the project, we used the current clamp recording to stimulate changes in the membrane potential of neurons. At this stage of the project, we simultaneously tested our electrophysiological equipment and equipment for digital fluorescence microscopy to assess the temporal resolution. To do this, we expressed fluorescent proteins in neurons that change fluorescence in the plasma membrane depending on the level of the membrane potential and developed software that can visualize these changes, similar to the calculated changes in QD fluorescence. During the third stage, we also calculated, selected and examined both the QD with the necessary properties and the optical filter system necessary for the optimal sensitivity of the proposed membrane potential measurement approach.5481 Product Description popup.authors Іванова С. Ю. Білан П.В. Борисюк А.Л. Войтенко Н.В. Довгань О. Дромарецький А.В. Кононенко М.І. Рибачук О. Степанюк А.Р. Шеремет Е.Ю. popup.nrat_date 2020-04-02 Close