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Information × Registration Number 0218U003266, 0115U002695 , R & D reports Title Effect of stromal microenvironment and its endocrine regulation of bone marrow hematopoiesis and state of bone tissue and in children with acute leukemia, who are affected by unfavorable factors of the Chernobyl accident popup.stage_title Head Bruslova Ekaterina Mihailovna, Registration Date 30-01-2018 Organization State institution "National research centеr for radiation medicine of the National academy of medical sciences of Ukraine " popup.description2 The object of study: 592 children (138 patients with acute leukemia, 454 persons in the comparison group-without oncolohematological pathology). The purpose:increasing the effectiveness of treatment children with of acute leukemia, affected by the adverse events of the Chernobyl accident, with changes in bone marrow hemopoiesis and the structural and functional status of bone tissue on the basis of the studi of stromal microenvironment and its endocrine regulation and the development of measures for the rehabilition of persons with gunshot wounds and bones fractures. Methods: clinical, immunological, cytological, biochemical, cultural, biophysical, statistical. The list of equipment is a hemoanalyzer, biochemical and amino asid analizers, an acid-alkaline analizer. The effectiveness of therapeutic measures in children with acute leukemia that are subject to unfavorable factors of the Chernobyl accident was scientifically proved and some mechanisms of radiation carcinogenesis were identified on the basis of evaluation of structural and functional changes in bone tissue end hemopoiesis and measures were developed for the rehabilitation of persons with gunshot injuries and fractures of bones Product Description popup.authors Ільєнко І.М. Базика Д.А. Володіна Т.Т. Гончар Л.О. Кузнєцова О.Є. Ляшенко Л.О. Пушкарьова Т.І. Трихліб І.В. Цвєткова Н.М. popup.nrat_date 2020-04-02 Close