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Information × Registration Number 0218U003606, 0117U003326 , R & D reports Title The role of vitamin D metabolism and homocysteine in changing the deformation properties of left ventricular and clinical efficacy homotsysteyindown-treatment and compensation of vitamin D in patients of coronary artery disease after revascularization popup.stage_title Head Nikonenko Alexander Semenovich, Registration Date 19-04-2018 Organization State Institute "Zaporizhzhia Medical Academy of Postgraduate Education of Ministry of Health of Ukraine" popup.description2 The study shows that a low level of vitamin D plays an important role in cardiovascular diseases, including CHD, congestive heart failure, valvular calcifications, stroke, hypertension. Vitamin D deficiency has many adverse effects, contributing to endothelial dysfunction, proliferation and migration of smooth muscle cells, calcification of the arterial wall; In addition, vitamin D deficiency has a detrimental effect on systemic conditions that contribute to the development of atherosclerosis, such as insulin resistance, ?-cell dysfunction, dyslipidemia. Thus, it can be argued that vitamin D deficiency has many effects on the function and pathology of cells and tissues involved in the atherogenic process. All patients with ischemic heart disease had vitamin D deficiency and hyperhomocysteemia, more pronounced with mufocal atherosclerosis, which should be taken into account when prescribing medication after myocardial revascularization. Product Description popup.authors Молодан Олександр Вікторович Одарюк Ольга Ігорівна Чмуль Карина Олегівна popup.nrat_date 2020-04-02 Close