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Information × Registration Number 0218U005279, 0116U006815 , R & D reports Title The study of changes in bone fractures by using a metal nanomaterials for osteosynthesis considering muscular function popup.stage_title Head Kuzenko Yevhen Victorovich, Registration Date 16-08-2018 Organization Sumy State University popup.description2 Subject of research - morphometric, microbiological indices and VAT of titanium plates of different configurations, morphological parameters and histochemical indices of bone tissue of a healthy human, and in conditions of osteoporotic changes, imitation 3D models with median and angular fractures of NSC and biomechanical characteristics of contacting biological bodies (fractions of NCH, chewing muscles) Methods of research - profilometry, scanning electron microscopy (CEM), microbiological research, histological, immunohistochemical research, computer tomography (CT), 3D computer modeling (СM) in the ANSYS program, mathematical methods. The purpose of the study is to create anatomic-functional plates, which includes the development of a method for optimizing the plates by taking into account the vectors of the muscle of the muscle. To achieve the goal, the following tasks were identified. Objectives of the study: 1. To define morpho-functional features of bone tissue . 2. To investigate the influence of ultrastructural and proliferative activity of bone marrow cells. 3. Explore microbiological adhesion to titanium plates with the correct surface roughness. 4. To develop the most optimal methods and algorithms of computer modeling for studying the stressed state of the plate strengthening fracture of the cortical bone. 5. To develop the most optimal plates for metallosteosynthesis of NT with taking into account vectors of action of its muscular device by computer simulation of the angular fracture. 6. Conduct a comparative assessment of the structures of the plates at the maximum stresses that arise under the action of chewing loads, and check the fixation reliability with the subsequent development of the plate with reduced area of the contact "bone - plate" and the thickness of the metal. Product Description popup.authors Голобородько Любов Вікторівна Гудименко Олена Олексіївна Дяченко Олена Олександрівна Закорко Інна-Маргарита Сергіївна Линдін Микола Сергійович Москаленко Роман Андрійович Некрасов Сергій Сергійович Сікора Владислав Володимирович Скиданенко Максим Сергійович Трейтяк Ігор Вікторович popup.nrat_date 2020-04-02 Close