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Information × Registration Number 0219U000022, 0116U000030 , R & D reports Title To study the mechanisms of intestinal colonization resistance disorders and metabolic functions of gut microbiota in patients with pyelonephritis, as a possible causes of recurrent pyelonephritis popup.stage_title Head Kolesnyk Mykola Oleksyovich, Registration Date 08-01-2019 Organization Institute of Nephrology Ukraine Academi Science of Medicine popup.description2 It was established significant increase in the resistance of the main pathogens of urinary system infections (E.coli and Enterococcus spp.) to antibiotics during past 10 years. It has been proved for the first time that the state of colonization resistance of the intestine of patients with pyelonephritis with hyperoxaluria, in comparison with patients without such, is characterized by a violation of the quantitative composition of microbiota. Deficiency of lactobacilli in the general composition of intestinal microbiotics activates oxidative stress. The efficacy of combined administration of Symbioform and Sodium nucleicinate in reducing oxalate excretion and preventing recurrence of pyelonephritis in women has been proved. Product Description popup.authors Акуленко І. Дріянська В.Є. Капустяк А.І. Козлюк Н.І. Король Л.В. Лебідь Л.О. Малишевська Н.М. Перейма О.Ю. Петрина О.П. Савченко В.С. Снісар Л.М. Сташевська Н.В. Степанова Н.М. Толстанова Г popup.nrat_date 2020-04-02 Close