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Information × Registration Number 0219U000057, 0118U000453 , R & D reports Title Development of new inhibitors of blood coagulation based on pharmacological agents that inhibit enzymatic activity of thrombin and factor Xa. popup.stage_title Head Tetyana Platonova, Registration Date 10-01-2019 Organization A.V.Palladin Institute of Biochemistry of National Academy of Sciences popup.description2 Using bioinformatics analysis, low-molecular substances specific to the active center of thrombin and factor Xa were selected. These substances were synthesized and characterized. Biological screening allowed us to choose substances that effectively inhibit blood plasma coagulation and can be the basis for creating a water-soluble high-affinity antithrombotic drug. Product Description popup.authors Горницька Ольга Володимирівна Гудзь Єгор Анатолійович Колєснікова Ірина Миколаївна Луговськой Едуард Віталійович Сломінський Олександр Юрійович Стогній Євген Миколайович Урвант Леся Петрівна Чернишенко Володимир Олександрович Чернишенко Тамара Мартинівна popup.nrat_date 2020-04-02 Close