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Information × Registration Number 0219U000065, 0115U002969 , R & D reports Title Study of enzymocytochemical and immunocytological features of hematopoietic progenitor cells at the different types of hemoblastosis popup.stage_title Head Gluzman Danylo Fishelevych, Доктор медичних наук Registration Date 10-01-2019 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 For the first time in chronic myelomonocytic leukemia (CMML), hematopoietic progenitor cells with various immunophenotypic signs were identified. The monoblast is characterized by the immunophenotype CD117-CD34-/+CD33+/-CD15-/+CD14- and a moderate reaction to an acid nonspecific esterase, for promonocytes with the immunophenotype CD117-CD34-CD33+/-CD15-/+CD14+/-, the pronounced cytochemical reaction is characteristic. Determining the precursor cells of the monocytic hematopoietic germ for cytomorphological, cytochemical features and recording the intensity of expression of myeloid antigens accurately defines the category and type of chronic myelomonocytic leukemia, are significant diagnostic markers of the disease for patients of older age groups and provides for the use of appropriate treatment protocols. Product Description popup.authors Іванівська Тетяна Степанівна Глузман Даниїл Фішелєвич Кірієнок Галина Валентинівна Коваль Стелла Володимирівна Петрусь Наталія Олександрівна Поліщук Альона Станіславівна Скляренко Лілія Михайлівна popup.nrat_date 2020-04-02 Close