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Information × Registration Number 0219U000764, 0116U003205 , R & D reports Title Develop treatment methods of patients with infective endocarditis caused by antibiotic resistant microorganisms popup.stage_title Head Krykunov Oleksiy Antonovich, Registration Date 25-02-2019 Organization M.M.Amosov National Institute of Cardio-Vascular Surgery of the Academy of Medical Sciences of Ukraine popup.description2 With the growth of antibiotic resistance of infective endocarditis pathogens, the use of complex methods is rational: combined with the principle of synergism etiotropic bactericidal antibiotic therapy, intraoperative use of antiseptic agents for the treatment of sites of infectious destruction, the avoidance, if possible, of synthetic material for the restoration of intracardiac anatomy, conduction of total body controlled hyperthermic perfusion during surgical intervention, additional appointment to antibiotic therapy of drugs with "antiquorum" action. Measures implemented in daily practice allowed to reduce the level of hospital mortality to 2.3% of cases and 0.5% of cases of relapses of the disease Product Description popup.authors Буряк Роман Вікторович Захарова Валентина Петрівна Колтунова Ганна Борисівна Крикунов Олексій Антонович Лучинець Олександр Федорович Мазур Олександра Анатоліївна Малишева Тетяна Анатоліївна Пустовалова Анна Олексіївна Сенько Олександр Григорович Списаренко Світлана Петрівна popup.nrat_date 2020-04-02 Close
R & D report
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Head: Krykunov Oleksiy Antonovich. Develop treatment methods of patients with infective endocarditis caused by antibiotic resistant microorganisms. (popup.stage: ). M.M.Amosov National Institute of Cardio-Vascular Surgery of the Academy of Medical Sciences of Ukraine. № 0219U000764
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Updated: 2026-03-28