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Information × Registration Number 0219U000890, 0118U005170 , R & D reports Title High-performance SPR spectrometer with sensor chip in the microarray format. Development of device and software. Section 2. Experimental exploitation. popup.stage_title Head Rachkov Oleksandr, Registration Date 13-03-2019 Organization Institute of Molecular Biology and Genetics of NASU popup.description2 To create DNA-sensor with sensor chip in the microarray format, it was necessary to select at least 3 oligonucleotide probes and three oligonucleotides-targets complementary to the probes. It was decided to use sequences that reproduce the fragments of the rpoB gene of M. tuberculosis, namely 1) normal, unmutated gene, 2) with mutation in codon 531, 3) with mutation in codon 526. Among the oligonucleotides having the lowest ability to undesirable intramolecular interactions, a 21-mer fragment (codons 525-531) was selected, and the corresponding three probes were named PNt, P2t and P3t. Product Description popup.authors Бахмачук Анна Олегівна Рачков Олександр Едуардович popup.nrat_date 2020-04-02 Close
R & D report
Head: Rachkov Oleksandr. High-performance SPR spectrometer with sensor chip in the microarray format. Development of device and software. Section 2. Experimental exploitation.. (popup.stage: ). Institute of Molecular Biology and Genetics of NASU. № 0219U000890
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Updated: 2026-03-26