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Information × Registration Number 0219U001050, 0117U000100 , R & D reports Title QSAR modeling and experimental studies of new bioactive compounds properties. popup.stage_title Head Metelytsia Larisa O., к.б.н. Registration Date 09-01-2019 Organization V.P. Kukhar Institute of bioorganic chemistry and petrochemistry popup.description2 In silico and in vitro, a series of thiazole-derived isoniazid derivatives have been identified as original anti-TB agents against multi-resistant Mycobacterium tuberculosis strains. Based on the developed QSAR models, a number of triphenylphosphonic salts of oxazole were selected and proposed as potential disinfectants with high anti-candidiasis activity against strains of multiresistant clinical isolates of the Candida genus. The rational design of the series of sulfanilamide derivatives of 1,3-oxazole has allowed to recommend a number of compounds as promising candidates for the development of new antitumor agents, tubulin inhibitors, with a specific molecular mechanism of action against a wide range of cancer pathologies.5481 Product Description popup.authors І.В.Семенюта В.В.Ковалішин Д.М.Година Л.Є.Калашнікова popup.nrat_date 2020-04-02 Close