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Information × Registration Number 0219U001387, 0116U007815 , R & D reports Title Study of the molecular-biological characteristics of endometrial cancer and determination of the endometrioid carcinoma molecular subtypes associated with high malignancy potential popup.stage_title Head Buchynska Liubov Georgiivna, Доктор біологічних наук Registration Date 28-01-2019 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology popup.description2 Based on clinico-morphological and genetic parameters of endometrial carcinoma (high proliferative activity, aneuploidy, low degree of differentiation and high invasive potential) more malignant variant of tumors were determined which characterized by lack of vimentine expression, overexpression of oncogenes c-Myc and Her-2/Neu and transcription factor E2F1. The obtained data are the fundamental basis for determining within a single morphological form - the endometrioid carcinoma of the endometrium - a distinct molecular subtype with a more aggressive course of the disease. Product Description popup.authors Брєєва О.В. Бучинська Л.Г. Глущенко Н.М. Горлакова О.О. Кашуба О.В. Кухарук Н.І. Лавренова А.О. Несіна І.П. Юрченко Н.П. popup.nrat_date 2020-04-02 Close