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Information × Registration Number 0219U001464, 0117U004639 , R & D reports Title Synthesis and study of the properties of new beta-keto-enol compounds and their metal complexes for the development of optical materials and fluorescent probes popup.stage_title Head Pekhnyo Vasyl Ivanovych, Registration Date 31-01-2019 Organization National Academy of Scienіses of Ukraine, Council of Productive Forces Studies of Ukraine popup.description2 A series of new functionalized beta-ketoneols was synthesized and investigated as probes for fluorescence detection of amyloid protein aggregates. Depending on the nature of the substituents, these dyes can increase the intensity of the emission to dozens of times in the presence of fibrillary aggregates, while they are less sensitive to native proteins. The sensitivity to amyloid aggregates depends both on the substituents on the amino group and on the nature of the aryl groups. A series of phthalocyanine complexes of zirconium and hafnium with ketoenol ligands have been obtained, their spectral-luminescent properties have been studied. The influence of the nature of the solvent on the intramolecular energy transfer was studied. It is established that the complexes obtained are able to absorb light in a wide range and transfer energy from the beta -Kethenol ligand to the phthalocyanine macrocycle. Product Description popup.authors Довбій Я.М. Ковальська В.Б. Лосицький М.Ю. Пехньо В.І. Третякова І.М. Царик Н.В. Черній В.Я. popup.nrat_date 2020-04-02 Close