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Information × Registration Number 0219U001876, 0116U004148 , R & D reports Title The pharmacological and pharmacogenetic aspects of the protective impact of immunobiological medications, enterosorbents, substances of natural and synthetic origin in various pathological conditions popup.stage_title Head Oleshchuk Oleksandra Myhaylivna, Registration Date 20-03-2019 Organization Horbachevsky Ternopil State Medical Academy popup.description2 R & D report: 98 p., 99 sources. SICKNESS DIABETES, MELATONIN, CHAMIERE VUSOLITIS, FITNESS MEDICINE, BLACKBERRY ORGANIC, CITOSTATIC MYELODAPPRESSION, MELFALAN, GRANULOCYTIC COLONYESTIMULIUJUIYA FACTOR, ENTESORPTION The object of the study - the features of pharmacotherapy of type 1 and type 2 diabetes and cytostatic gonadotoxicity, the study of the effectiveness of colony-stimulating factor preparations on the model of cytostatic myelogenous depression. The purpose of the work is to find out the peculiarities of the influence of melatonin on the parameters of prooxidant-antioxidant homeostasis in blood and liver of healthy animals and carbohydrate metabolism, liver status, lipid peroxidation processes, antioxidant defense status, immunological status in experimental diabetes 1 and 2 types. To study the peculiarities of the effect of melatonin on the liver status in patients with non-insulin-dependent diabetes mellitus, to determine the role of the melatonin receptor polymorphism in hepatoprotective action of melatonin. To study the pharmacological properties of extracts of the medicinal case and chamomile of the pericarp. To find out gonadoprotective effects of enterosorption on the background of cytostatic therapy. To investigate the myeloprotective activity of the original domestic preparation of the recombinant granulocyte colony stimulating factor and officinal preparation filgrastim on the model of myelodecpression caused by cytostatic melphalanum. Product Description popup.authors Іванків Яна Ігорівна Вольська Аліна Станіславівна Драпак Оксана Ярославівна Коваль Марія Іванівна Курило Христина Іванівна Луканюк Маряна Ігорівна Мосейчук Ірина Петрівна Олещук Олександра Михайлівна Пида Віктор Петрович Посохова Катерина Андріївна Фещенко Галина Іванівна Черняшова Валентина Володимирівна Чорномидз Андрій Васильович Шевчук Оксана Олегівна popup.nrat_date 2020-04-02 Close