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Information × Registration Number 0219U003444, 0116U001633 , R & D reports Title Prooxidant antioxidant homeostasis and membrane transport systems of bioobjects under the influence of physicochemical factors popup.stage_title Head Sanagursky Dmytro Ivanovych, Registration Date 14-02-2019 Organization Ivan Franko National University of Lviv popup.description2 Flurenizide has been shown to increase the content of lipid hydroperoxides to the tenth division of blastomeres of the Misgurnus fossilis L. fungus embryos. Fluurenizide at concentrations of 0.01; 0.05; 0.15 and 1 mM leads to an increase in the content of TBА-positive products. The development stage of the development of germs of 16 blastomeric mucus is susceptible to flurenizide, whereas stage 256 blastomeres are least susceptible. Fluinizide affects the structure of mitochondria and the endoplasmic net, leading to an increase in the number of lysosomes in the embryos of the liver; the severity of the changes is dose-dependent. It was established that the most sensitive to the action of 1,4-naphthoquinones derivatives is superoxide dismutase, whereas the least sensitive is glutathione peroxidase. The derivatives of 1,4-naphthoquinone result in a dose-dependent decrease in the activity of Na +, K + -ATPase and Ca2 + -ATPase of the embryos of the liver. It was found that hypodermic administration of histamine in rats causes reduction of lumen of alveoli, increase of thickness of interalveolar partitions, spasmation of bronchioles, decrease of the area of the renal corpuscles, vascular glomeruli, decrease of the lumen of the proximal and distal convoluted tubules in the cortical kidney and perivascular edema around the vessels, swelling of the mitochondria, vacuolization of the endoplasmic nets, increase in the number of peroxisomes and lysosomes. Pouring sodium hypochlorite into animals causes dystrophic changes, enlargement of the connective tissue of the lungs, increase in the area, as well as the larger and smaller axis of the vascular glomeruli in the kidneys. Product Description popup.authors Боднарчук Наталія Олександрівна Бура Марта Володимирівна Галан Марія Богданівна Гарасим Наталія Петрівна Генега Анастасія Богданівна Дика Марія василівна Отчич Віра Петрівна Санагурський Дмитро Іванович Семочко Олена Миколаївна Тарновська Антоніна Володимирівна Яремчук Марія Михайлівна popup.nrat_date 2020-04-02 Close