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Information × Registration Number 0219U004537, 0114U000933 , R & D reports Title Elaboration of improved diagnostic and therapeutic directions on the ground of studying functional and organic components of development of digestive system pathology popup.stage_title Head Stepanov Yuriy Mironovich, Registration Date 03-09-2019 Organization Dniepropetrovsk State Medical Academy popup.description2 It has been established that in non-alcoholic fatty liver disease in conditions of significant fibrosis (F3), an increase in cholestasis is observed, the expediency of conducting elastometry of the liver with the apparatus of FibroScan, which is more sensitive in determining fatty dystrophy than ultrasound, has been proved. The deficiency of selenium in gastroenterological patients occurs in 40% of cases; deflection of indicators of glutathione peroxidase, malonic dialdehyde, ceruloplasmin are noted both in the direction of increase and decrease, normal values ??were noted only in 11.4% of patients, in the background of treatment with cefasel in 100% of cases there was a correction of selenium deficiency to normal values, the average level of selenium after 1 month of treatment was 106.3 ± 17.92 ?g / l. Using modern methods of endoscopy (narrow-spectral endoscopy of NBI and endoscopy in white with image enlargement and chromoscopy) by 21.5%, it is possible to detect precancerous stomach states. There is a tendency towards a higher frequency of excess bacterial growth syndrome in patients with ulcerative colitis in comparison with Crohn's disease. In patients with chronic reflux gastritis, elevated levels of bile acids in gastric juice have been detected, in comparison with healthy individuals, regardless of the background cause of reflux, in the presence of atrophy in the mucous membrane of the stomach in patients with reflux gastritis, a significant increase in the average level of bile acids in comparison with the indicators was found. healthy individuals. Product Description popup.authors Будзак Ігор Ярославович Власова Оксана Миколаївна Кононов Ігор Миколайович Косинська Світлана Валеріївна Саленко Альбіна Володимирівна Шендрик Любов Михайлівна popup.nrat_date 2020-04-02 Close