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Information × Registration Number 0219U005635, 0116U004474 , R & D reports Title Mechanisms of development and compensation hypoxic and oxidative tissue damage in neurodegenerative and metabolic disorders popup.stage_title Head Mankivska Iryna M., Portnychenko Alla G., Mankovska Iryna М., Доктор медичних наук Registration Date 26-12-2019 Organization Bogomolets Institute of Physiology, National Academy of Sciences of Ukraine popup.description2 In experimental and clinical studies the mechanisms of disorders of oxygen supply of tissues and cytoprotection in type 2 diabetes, neurodegenerative diseases (Parkinson's and Alzheimer's disease), cerebral hypoperfusion, extreme effects associated with mitochondrial dysfunction, IG dysfunction, IG -1 / SIRT-dependent signaling pathways. Experimental models of type 2 diabetes, apical balloon myocardial dysfunction have been developed. The mode of hypoxytherapy of patients with initial stages of Alzheimer's disease has been developed. Product Description popup.authors І.В.Пономарьова І.М.Маньковська І.О.Барановська А.Г.Портниченко А.М.Сидоренко А.С. Шаповалова Бакуновський О.М. Братусь Л.В. В.І.Портніченко В.В.Бабічева Гончар О.О. Дубова М.Г. К.Р.Тимошенко Л.Я. Топчанюк Лінник О.О. М.І.Василенко Моісеєнко Є.В. О.Ю.Гарматіна П.К. Цапенко Р.Б. Алієв Розова К.В. Серебровська Т.В. Ю.В.Путій popup.nrat_date 2020-04-02 Close