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Information × Registration Number 0219U006223, 0112U005642 , R & D reports Title Role of infringement of mutural relations lymphoid and epithelial immune system compartments of mucosas in development of an experimental pathology popup.stage_title Head Kamishnij Oleksandr Mikhajlovich, Доктор медичних наук Registration Date 24-04-2019 Organization Zaporozhye State Medical University. Department of psychiatry popup.description2 With the use of modern molecular genetic and immunofluorescence methods, key immune links of development and progression of experimental inflammatory diseases of the intestine, experimental diabetes mellitus and chronic social stress have been identified. The peculiarities of expression in the experimental pathology of the congenital immune receptors TLR2, TLR4, NOD2 and RIGI by adaptive lymphocyte cells are revealed. It has been established that the development of experimental pathology in rats is accompanied by an increase in the level of mRNA of proinflammatory cytokines IL-1? and IL-17A, NLRP3-inflamasomy, FFAR2 receptor, and alarmin HMGB1. Product Description popup.authors Деген Анна Сергіївна Жеребятьєв Олександр Сергійович Камишний Олександр Михайлович Топол Інна Олександрівна popup.nrat_date 2020-04-02 Close