Search academic texts

Information × Registration Number 0219U100953, 0118U102391 , R & D reports Title Investigation of the interaction of curcumin with cellular targets and the selection and creation of its functionally effective forms for the treatment of neurodegenerative diseases popup.stage_title Head Yemets Alla I., Доктор біологічних наук Registration Date 08-04-2019 Organization Institute of Food Biotechnology and Genomics of the National Academy of Sciences of Ukraine popup.description2 Human α-tubulin has been identified as the most likely target of curcumin. Screening of the whole surface of human alpha tubulin has been performed, a series of most likely sites for binding of curcuminoid have been identified. Created a natural curcuminoid library. The conditions for the formation of the liposomal form of curcumin (dierguloylmethane) have been investigated. The methods for obtaining and determining the size of liposomes and the percentage content of curcumin in the liposomes are given. Product Description popup.authors Andriyash Ganna S. Bayer Oleh O. Beiko Natalia Ye. Blume Yaroslav B. Horiunova Inna I. Demchuk Oleh M. Karpov Pavlo A. Kravets Olena A. Novozhilov Dmitry О. Ozheredov Sergey P. Pydiura Nikolay Plokhovska Svitlana Rayevsky Olexey V. Samofalova Dariya O. Spivak Svetlana I. Tigunova Helen Shulga Sergey M. popup.nrat_date 2020-04-02 Close