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Information × Registration Number 0219U101617, 0119U101914 , R & D reports Title The effect of circulating viral transactivator proteins (HIV-1 Tat and EBV Zta) on gene expression in B-cell lymphomagenesis popup.stage_title Head Skrypkina Inessa Ya., Кандидат біологічних наук Registration Date 27-09-2019 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description2  As a result of the Phase 1 research, the following studies were performed: Recombinant plasmids were generated to produce native proteins and Zta (EBV) and Tat (HIV-1) mutants in the pET28a vector, and constructs for knockout vector pCD28 and overexpression based on the lentiviral vector pCD -CMV-MCS-EF1-copGFP and CRISPR pSpCas9 (BB) -2A-Puro systems, respectively. Skripkina I.Ya. and Shabliy VA visited a French laboratory where they received appropriate designs and discussed their future joint experiments. In turn, the Ukrainian group hosted a project manager from the French side, Yegor Vassetzky, to review and discuss the work. Product Description popup.authors Areshkov Pavlo O. Skrypkina Inessa Ya. Shablii Volodymyr A. popup.nrat_date 2020-04-02 Close