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Information × Registration Number 0219U101981, 0115U003633 , R & D reports Title Investigation of mesenchymal stem cells regenerative potency in perinatal pathology of CNS popup.stage_title Head Skibo Galyna G., Доктор медичних наук Registration Date 05-12-2019 Organization Bogomolets Institute of Physiology popup.description2 Immunohistochemical analysis revealed that on the 30th day, GFP-positive MMSCs transplanted in in vivo modeling of PVL retained their phenotypic characteristics, remained in an undifferentiated state and did not express markers of mature neurons and glial cells. In in vitro model it was shown that on the 14th day of GFP-positive MMSCs coculturing of with organotypic brain slices, a significant amount of MMSCs survived, maintained phenotypic characteristics and remained in an undifferentiated state. Approximately 5% of GFP-positive MSCs differentiated into NeuN-positive mature neurons or oligodendrocytes  Product Description popup.authors Lushnikovа Irina V. Pacseva Marina A. Skibo Galina G. Tsupykov Oleg M. popup.nrat_date 2020-04-02 Close