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Information × Registration Number 0219U101996, 0114U001997 , R & D reports Title Development and improvement of diagnostic methods, complex treatment and prevention proceedings of patients having pathology of dental and jaw system. popup.stage_title Head Belyaev Eduard V., Registration Date 11-12-2019 Organization Vinnytsia National Pirogov Memorial Medical University popup.description2 Object of study: the process of orthopedic treatment of patients with complete and partial loss of teeth and clinical use of removable dentures with depreciation properties; mineral enamel density of teeth, wear resistance of restorative dental materials and natural teeth, oral fluid, nuclear DNA status and proliferative activity of patients' oral cavity epithelial cells. Subject of research: means and methods of orthopedic treatment of patients. Purpose of the research: to develop new and improve existing methods of diagnostics, protocols of complex treatment and prevention of patients with pathology of the dental-jaw system. To increase the effectiveness of orthopedic treatment of patients with tooth loss with different types of dentures. Research methods: experimental, clinical, physical, biophysical, flow cytometry, cytological, microbiological, biochemical, psychological, sociological, statistical. Scientific data on increase of negative effect of PRD with acrylic bases in comparison with thermoplastic ones on salivary velocity, pH level, buffer capacity of mouth fluid and its viscosity have been added, which contributed to deterioration of oral hygiene and health of patients with MPS index. For the first time, the results of DNA cytometry revealed a high intensity of proliferation and renewal of buccal epithelial cells in control subjects. It was proved that the indexes of intervals of the major phases of DNA separation and the state of cell apoptosis in patients using PPT with thermoplastic bases had no statistically significant difference with respect to the control group. Different variants of CRD designs and methods of their production that have depreciation properties are scientifically substantiated and tested, which ensures a balanced distribution of chewing load on the prosthetic bed and enhances their functional quality and speeds up the adaptation process. Product Description popup.authors popup.nrat_date 2020-04-02 Close