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Information × Registration Number 0219U102304, 0115U002926 , R & D reports Title The creation and selection of highly productive cell lines the representatives of genus Lysimachia L. for the needs of pharmacology. popup.stage_title Head Radchenko Volodymyr H., Registration Date 26-12-2019 Organization Institute for evolutionary ecology NAS Ukraine popup.description2  The purpose of the work is a comprehensive study of the biological, anatomical, cytological, biochemical and molecular genetic features of the representatives of the genus Lysimachia common in Ukraine and the identification of promising species and their selection lines for obtaining highly productive samples for the content of biologically active substances in raw materials, particularly vegetable oil pharmacology, as well as enriching biodiversity and rational use of natural resources. The high prospects of using Lysimachia nummularia L. plants for pharmacological needs, in particular, as a source of embelin and flavonol myricetin, have been established. Miritsetin has a high biocidal activity against gram-positive and gram-negative bacteria and is able to perform the function of phytoantibiotic. Five cell lines of Lysimachia nummularia L. were selectively selected. Stilbenoids and one cell line with high productivity of synthesis and accumulation of myricetin in callus tissues were actively synthesized. A technique has been developed for the production of pharmaceutically valuable raw materials in vitro that deserves further use on an industrial scale. Product Description popup.authors Bilous Svitlana Yu. Gonchar Ganna Yu. Likhanov Artur Fedorovich Leshchenjuk Olena M. Mazura Marina Yu. Матiashuk Raisa K. Radchenko Volodymyr G Yurchuk Mikola I. popup.nrat_date 2020-04-02 Close