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Information × Registration Number 0220U000575, 0115U004127 , R & D reports Title Reproduction features of human DNA-containing viruses upon influence of potential antiviral agents popup.stage_title Head Zagorodnya Svetlana Dmitrivna, Кандидат біологічних наук Registration Date 12-03-2020 Organization Zabolotny Institute of Microbiology and Virology Ukrainian NAS popup.description2 The biological activity of 30 newly synthesized fluorinated compounds of nucleoside and nucleotide nature was studied. Anti-adenovirus activity was detected by substances based on the chloro-substituted furan cycle, the titer of the synthesized de novo virus decreased by 98%. Effective inhibition of the reproduction of HSV-1 by triazole derivatives in the in vitro and in vivo systems has been demonstrated (100% efficiency index). Some fluorinated have both polyvalent and monospecific effects on human adenovirus and herpesviruses and may be prototypes for the creation of new etiotropic drugs Product Description popup.authors Білявська Л. Баранова Г. Загородня С.Д. Затовська Т. Науменко К. Паньківська Ю. Повниця О. popup.nrat_date 2020-07-03 Close