Search academic texts

Information × Registration Number 0220U001082, 0117U000422 , R & D reports Title The molecular-genetic and antigenic monitoring of influenza viruses in Ukraine popup.stage_title Head Mironenko Alla Petrivna, Доктор медичних наук Registration Date 22-01-2020 Organization The L.V.Gromaschevskyi Scientific and Research Institute of Epidemiology and Infectious Diseases popup.description2 Final report on scientific research work: 91 pages, 3 charts, 31 drawings, 42 sources.The aim of work was the identification of genetic, antigenic changes and etiological forecasting by carrying out molecular-genetic and antigenic monitoring of influenza viruses.The object of research is the epidemic process of influenza, influenza strains, genetic sequences of influenza virus RNA, amino acid sequences of influenza virus proteins.The methods of research are: epidemiological, virological, serological, molecular-genetic, bioinformatics, statistical.For the first time in Ukraine there was identified the etiological structure of human influenza viruses' population of seasons 2016-2017, 2017-2018, 2018-2019, which were caused predominantly by influenza viruses A(H1N1)pdm, A(H3N2) and B.There was performed phylogenetic analysis and created the phylogenetic trees using the results of genome sequencing of influenza viruses 2016-2019.There was performed the 3D modeling of surface proteins of influenza viruses A(H3N2) and A(H1N1)pdm, influenza B viruses, lineage B/Victoria and B/Yamagata.INFLUENZA, EPIDEMIC FORECAST, INFLUENZA VIRUSES, PHYLOGENETIC ANALYSIS, 3D MODELING. Product Description popup.authors Голубка О.С. Лейбенко Л.В. Радченко Л.В. popup.nrat_date 2020-04-02 Close