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Information × Registration Number 0220U100005, 0117U004534 , R & D reports Title To learn the nosotropic mechanisms of forming of allergic defeats of gastroenteric highway for the children of early age with a food hypersensitiveness popup.stage_title Head Shadrin Oleh H., Доктор медичних наук Registration Date 02-01-2020 Organization SI «Institute of Pediatrics, Obstetrics and Gynecology named academician O. M. Lukyanovaya NAMS of Ukraine» popup.description2 The study has established the peculiarities of the clinical course of allergic lesions of the gastrointestinal tract in children of early age, depending on the mechanisms of development of immune reactions and certain causes of food allergens. The methods of conducting an open oral provocative sample with the non-lactose mixture and application patch tests have been introduced into the pediatric practice. The imbalance of fatty acids of blood is set on the examined children, indicating the proinflammatory orientation of lipids metabolism. High concentrations of serum cytokines IL-5 and TNF-α are found, which correlate with the activity of allergic inflammation according to morphological research. The expanded presentation of the pathogenesis of the gastrointestyonal HA in children of young age-for the first time there is a reliable increase in them of lipid mediators allergy (Leukotrians) in various biological mediums and performance assessment Individualised Leuktriene receptor inhibitors in the complex treatment. Improved diagnostic morphological and immunohihichemical criteria of allergic inflammation of the gastrointestinal tract. The algorithm of the gastrointestinal diagnostics in children of early age has been developed.   Product Description popup.authors popup.nrat_date 2020-04-02 Close