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Information × Registration Number 0220U100093, 0115U002969 , R & D reports Title Study of enzymocytochemical and immunocytological features of hematopoietic progenitor cells at the different types of hemoblastosis popup.stage_title Head Gluzman Danilo F., Доктор медичних наук Registration Date 09-01-2020 Organization R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology National Academy of Sciences of Ukraine popup.description2 The precise diagnosis of the variants of acute lymphoblastic leukemias that differ clinically and prognostically based on the immunocytochemical detection of the expression of pathognomonic antigens of B-lymphoblasts (CD19, CD22, CD10, CD20, CD79α, CD58), T-lymphoblasts (CD7, CD2, CD3, CD4, CD8, CD5) as well as expression of non-specific myeloid markers (CD34, CD33, CD13) allowed for the identification of the pathological clone of cells, which are close to the leukemic stem cells with CD34+/-CD33-/+CD19+/- immunophenotype. The presence of the said immunophenotype is considered as a marker feature delineating the group of patients with unfavorable course of the disease. The results of the scientific development have been put into clinical practice of the hematological departments of Kyiv municipal clinical hospital No. 9 and Communal institution "Kyiv municipal clinical hospital No. 4 of the Dnipro City Council". Product Description popup.authors Ivanivska Tetiana S. Gluzman Danilo F. Zavelevych Mykhailo P. Kiriienok Galyna V. Koval Stella V. Petrus Nataliia O. Polishchuk Aliona S. Skliarenko Liliia M. popup.nrat_date 2020-04-02 Close