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Information × Registration Number 0220U100197, 0117U006710 , R & D reports Title Mechanisms of the development of hypoxic state under nitrite methemoglobinemia popup.stage_title Head Sydoriak Natalia H., Registration Date 13-01-2020 Organization Bogdan Khmelnitsky Melitopol State Pedagogical University popup.description2  The work obtained data on the effect of sodium nitrite in different doses on the main indicators characterizing external respiration, blood oxygenation, oxygen transport function of blood, depending on the time of exposure to the hemoglobin former - sodium nitrite in doses of 3 and 5 mg per 100 g of animal body weight. For the first time, a characteristic of the oxygen regimes of the body is given and its numerical values are obtained under conditions of the development of chronic methemoglobinemia. The features of changes in O2 transport in the body in rats with the development of chronic nitrite methemoglobinemia of varying severity were revealed. The levels of oxygen parameters at which oxygen delivery to tissues is disturbed during methemoglobinemia lead to the development of a hypoxic state. The main causes and mechanisms of the development of a hypoxic state with nitrite methemoglobinemia of varying severity were identified. Product Description popup.authors popup.nrat_date 2020-04-02 Close