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Information × Registration Number 0220U100531, 0115U001358 , R & D reports Title The development of biotechnological wound coverings for application in medicine popup.stage_title Head Lukash Lyubov L., Доктор біологічних наук Registration Date 21-01-2020 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description2 It has been developed and optimized a cell technology of receiving thermal coverings and has been created biodesigns "membrane-gel-cell" and "gel-cell", intended for treatment of burn wounds using in vivo models. It has been characterized the survival and the indices of the cells immobilized in gel, which can be expanded in culture as established cell lines. It is shown that cellular xenotransplantants of various origin (skin, peripheral blood, embryonal germ cells) are effective as thermal coverings at treatment of thermal burns of IIIb degree on two animal models (linear rats and mice). It is created biodesigns in which instead of a cellular component we used the acellular medium, conditioned by the cells. Use of cell cultures as producers of a complex of biologically active agents stimulating healing of burn wounds has certain advantages before cell transplantations due to decrease in prime cost of drug, simplification of store technology, use, standardization and safety control, an exception of the risks connected with transplantation of cells. Product Description popup.authors Kushniruk Veronica O. Macewicz Larysa L. Papuga Alexander Ye. Ruban Tetyana P. popup.nrat_date 2020-04-02 Close