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Information × Registration Number 0220U100797, 0117U002350 , R & D reports Title Genetic determination of preventive approaches in noncarrying of pregnancy popup.stage_title Head Yuzko Oleksandr M., Registration Date 28-01-2020 Organization HSEE of Ukraine "Bukovinian State Medical University" popup.description2  Object of study: the main indicators of the fetal state, fetoplacental complex state, AGTR1 gene polymorphism in pregnant women with miscarriage; peculiarities of the course of pregnancy, childbirth and postpartum period in pregnant women with miscarriage; cumulative influx and correlation of pregnancy risk factors. Purpose: To substantiate and evaluate the effectiveness of the introduction of medical and preventive measures in pregnant women with a history of miscarriage, taking into account the polymorphism of the gene AGTR 1 and its effect on embryometric, hormonal, immunological parameters. Methods of study: analysis of anamnestic data, clinical examination, general clinical, instrumental (ultrasound, Doppler), histological, enzyme-linked immunosorbent assay in the serum of pregnant, genetic, statistical. Installed. For the first time, based on a comprehensive study of ultrasound markers of the fetus and fetoplacental complex, indicators of hormone levels and polymorphism of the gene AGTR 1, a pathogenetically sound complex approach to preventive measures and individualized basic treatment for pregnancy, life-changing, and higher pregnancy rates are developed, perinatal losses and the birth of deeply premature babies. For the first time, the effect of miscarriage gene polymorphism on the course and outcome of pregnancy was conducted, which allows us to predict the possible negative consequences at an early date. The results obtained will allow timely selection of treatment-and-prophylactic tactics in this group of pregnant women, avoiding polypragmasia and delayed standard basic treatment. Product Description popup.authors Kalinovskaya Irina V. Yuzko Oleksandr M. popup.nrat_date 2020-04-02 Close