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Information × Registration Number 0220U101390, 0118U005172 , R & D reports Title Intelligent biosensor systems for determination of some metabolites to control the social important human diseases. Section 1. Creation of electrochemical enzyme biosensors for analysis of metabolites popup.stage_title Head Soldatkin Oleksii P., Доктор біологічних наук Registration Date 10-02-2020 Organization Institute of Molecular Biology and Genetics of NAS of Ukraine popup.description2  Optimization of the method of immobilization of enzymes (GOD, urease) on the surfaces of physical transducers, including the use of nanoparticles of different nature (gold nanoparticles and nano- and microparticles of zeolites), was carried out. The ratio of components of bioselective membranes of biosensors based on immobilized by different methods of enzymes creatinine deiminase, glucose oxidase and urease is selected. The technique of using immobilized enzymes for the simultaneous determination of major metabolites (glucose, urea, creatinine) has been worked out. The optimal working conditions of immobilized enzymes for preserving the activity of both the enzymes themselves and preserving the performance characteristics of the transducers are investigated and their basic characteristics are studied. Product Description popup.authors Arkhypova Valentyna M. Dziadevych Sergii V. Mruga Daryna O. Саяпіна Ольга Ярославівна Shkotova Liudmyla V. popup.nrat_date 2020-04-02 Close