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Information × Registration Number 0220U102427, 0117U000479 , R & D reports Title To develop diagnostic algorithm of vascular disorders in patients with metabolic syndrome and obesity popup.stage_title Head Orlenko Valeriya L., Кандидат медичних наук Registration Date 13-03-2020 Organization State Institute "V.P. Komissarenko Institute Of Endocrinology And Metabolism of The National Academy of Medical Science of Ukraine" popup.description2  The object: obesity, first discovered type 2 diabetes, the main vessels, diabetic neuropathy, diabetic retinopathy. Purpose: to develop personalized approaches to the diagnosis and correction of hormonal and metabolic disorders in patients with diabetes mellitus, depending on phenotypic features, and to substantiate appropriate approaches to treatment. Methods: clinical, laboratory, statistical. Theoretical and practical results. th type 2 diabetes with overweight and obesity revealed compaction and thickening of the walls of the brachiocephalic vessels, 52.27% of patients revealed hemodynamically significant stenoses due to the development of atherosclerotic plaques in the extracranial division of the vessels of the carotid wall. endothelial dysfunction according to flow-dependent vasodilation of the brachial artery, indicating a violation of the compensatory capacity of regional blood flow. When conducting a quantitative assessment of blood flow through the vessels of the kidneys according to Doppler, the signs of vessel rigidity in the form of a decrease in the velocity indicators of blood flow, as well as an increase in the resistance index are determined. The data on the efficiency of the use of autologous cells of the stromal-vascular fraction of adipose tissue for the treatment of critical limb ischemia in patients with obesity diabetes and overweight individuals without disturbing carbohydrate metabolism were obtained. Product Description popup.authors Ivaskiva Kateryna Yu Bolgarska Svitlana V Gamezardashvilli Iryna V. Dobrovynska Olena V Solovey Maryana L Tron'ko Kateryna M popup.nrat_date 2020-04-01 Close