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Information × Registration Number 0220U102499, 0117U002579 , R & D reports Title The role of peptidergic structures of hypothalamus and brain stem in the pathogenesis of arterial hypertension. popup.stage_title Head Kolesnyk Yurii M., Доктор медичних наук Registration Date 16-03-2020 Organization Zaporizhzhya State Medical University popup.description2  It was first determined that in rats with formed hypertension, regardless of the etiology and pathogenesis of its formation, there are the same changes in the content of pressor and depressor neuropeptides in the investigated nuclei of hypothalamus, which are characterized by a decrease in levels of brain natrihydrogenesis, . It is proved that the peculiarities of their content and balance depend on the etiopathogenetic mechanisms of the formed pathology. Thus, in comparison with the control, endocrine-saline arterial hypertension shows a significant predominance of the content of depressant neuropeptides over the pressor 4.3 times, while in the model of essential arterial hypertension - almost three times. Product Description popup.authors Ivanenko Taras V Abramov Andrii V Bessarab Heorhii I Hancheva Olha V Hrekova Tetiana A Zhulinskyi Volodymyr O Kovalov Mykola M Melnykova Olha V Tishchenko Serhii V Tishchenko Serhii V popup.nrat_date 2020-04-01 Close