Search academic texts

Information × Registration Number 0220U102667, 0118U000923 , R & D reports Title Optimization of diagnosis and treatment of comorbid diseases (hypertension and type 2 diabetes) based on the evaluation cardiogemodinamic, metabolism and farmakohenetyc analysis popup.stage_title Head Knyazkova Iryna I., Доктор медичних наук Registration Date 24-04-2020 Organization Kharkiv National Medical University popup.description2  The indicators characterizing the functions of the left ventricular myocardium and renal parenchyma were analyzed in patients with GC and type 2 diabetes without complications and control group and the algorithm of examination of this cohort of patients was optimized. New data on the diagnostic value of determination of serum cystatin C in patients with hypertension and type 2 diabetes have been obtained. High informativeness of this indicator for the assessment of the functional state of the kidneys in patients with hypertension and type 2 diabetes has been revealed. Significance of cystatin as a marker of the formation of diabetic nephropathy in patients with hypertension was determined. The pathological imbalance of adipokine profile, namely, decreased levels of omentin, C? 2G, glypican-4, and increased serum levels of visfatin in patients with GC and type 2 diabetes, as compared with healthy examinations and comparison groups, have been shown to be associated with remodeling processes and blood vessels , and the HLS itself and the thickening of the SAA team. The role of adipokine imbalance on the development of disorders of carbohydrate and lipid spectra in patients with GC has been determined. The effectiveness of the combination of lisinopril and carvedilol in the standard therapy of patients with GC and type 2 diabetes in all variants of the polymorphic marker 2350 A / G of the ACE gene Product Description popup.authors Ilchenko Iryna A. Abramova Lilia P. Al-Travnekh Olena V. Bilovol Olexander M Denysenko Viktor P. Zlatkina Vira V. Kyryenko Oleksandr M. Korniychuk Vladyslav I. Nemtsova Valeria D. popup.nrat_date 2020-07-03 Close