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Registration Number

0220U103011, 0115U005285 , R & D reports

Title

Regional specialities of expansion, clinical presentations and efficacy of treatment of internal organs in patients from different altitudes zones of Transcarpathia.

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Head

Rishko Mykola V., Доктор медичних наук

Registration Date

13-07-2020

Organization

State University "Uzhhorod National University"

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It was established the relationship between the condition of the coronary artery in people with coronary heart disease and altitude of residence (residents of mountain and plain settlements), the prevalence of risk factors in these populations, comorbidities, electrocardiographic and echocardiographic parameters, exercise tolerance, laboratory changes, particular, the lipid and fatty acid spectrum. It have been identified.predictors of intact coronary arteries and stenotic lesions of the coronary artery. It was identified Certain categories of inhabitants of mountain and plain settlements with a very high probability of stenotic coronary sclerosis. It have been proposed prognostic criteria, which in mountain dwellers were associated with high levels of pro-inflammatory and proatherogenic fatty acids. Such individuals should determine the levels of fatty acids in the blood plasma, which will allow the initial pro-inflammatory and atherogenic changes in the body. The decrease in eicosapentaenoic LC levels and the total concentration of ω3 PUFA while maintaining a high level of arachidonic LC should be considered as a predictor of a high risk of coronary blood flow disorders. 

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Kedyk Antonina V.
Kutsyn Oleksandr O
Rishko Mykola V.
Ustych Olena V

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2020-10-01