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Information × Registration Number 0220U104273, 0120U102682 , R & D reports Title Study of new mechanism of protofibrils’ branching during the formathon of three-dimensional fibrin network – the core of thrombus. popup.stage_title Head Chernyshenko Volodymyr O., Кандидат біологічних наук Registration Date 15-12-2020 Organization Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine popup.description2 It was shown the possibility of the insertion of D-region of neigbouring fibrin molecule or protofibril in the DDE-triad in the process of protofibril formation, that is acting on the structure of protofibrils, fibrils and is supporting their branching. It was proven that interaction of additional D-region in the DDE-triad occurs thanking to one of B-knobs. Sites involved in such interaction can be assumed as the potentional targets of antitrombotic drugs.  Product Description popup.authors Grabovskiy Oleksiy O. Stohnii Evgen M. popup.nrat_date 2020-12-15 Close