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Information × Registration Number 0220U104341, 0120U103978 , R & D reports Title Design, synthesis and activity of calixarene derivatives as inhibitors of protein tyrosine phosphatases and other enzymes popup.stage_title Head Kalchenko Vitaly I., Доктор хімічних наук Registration Date 16-12-2020 Organization Institute of Organic Chemistry NAS of Ukraine popup.description2 Optimal methods for the synthesis and synthesis of N, N-dialkylsulfonylamido-tiacalix[4]arenes and N, N-dialkylsulfonylamidosulfocalix[4]arenes were developed. The bioactivity of sulfamide derivatives of tetrahydroxycalix[4] arene, thiacalix[4]arene and sulfonylcalix[4]arene was evaluated.N, N-diethyl- and N, N-dibutylsulfamides have been shown to be potent inhibitors of human protein tyrosine phosphatases, known as targets for treatment of many diseases. Product Description popup.authors Buldenko Vladislav M Vovk Andriy I Kalchenko Vitaly I Kobzar Olexandr L Cherenok Sergiy O Shulga Yuriy V popup.nrat_date 2020-12-16 Close
R & D report
Head: Kalchenko Vitaly I.. Design, synthesis and activity of calixarene derivatives as inhibitors of protein tyrosine phosphatases and other enzymes. (popup.stage: ). Institute of Organic Chemistry NAS of Ukraine. № 0220U104341
1 documents found

Updated: 2026-03-22