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Information × Registration Number 0220U104356, 0118U000111 , R & D reports Title Screening of the secondary metabolites of streptomyces active for polyresistant nosocominal infections agents popup.stage_title Head Korniichuk Olena P, Registration Date 16-12-2020 Organization Danylo Halytsky Lviv National Medical University popup.description2  Object of research: cultures of microorganisms of different groups - gram-positive and gram-negative bacteria, yeast and molds The subject of the study is to investigate the type and level of antibiotic resistance of microorganisms isolated in various infectious processes, including catheter-associated infections. To investigate the ability of the obtained clinical isolates of microorganisms to form a biofilm structure. Carry out screening and detailed study of antimicrobial activity of the obtained extracts with determination of the minimum inhibitory concentration of drugs. Conduct research to determine the rate of acquisition of resistance to these substances Identify active secondary metabolites of streptomycetes against topical multidrug-resistant pathogens of nosocomial infections. method of studying new drugs with antibiotic properties obtained by extracting cultures of actinomycetes using appropriate test cultures of microorganisms Tasks of work: Isolate from patients cultures of microorganisms of different groups - gram-positive and gram-negative bacteria, yeast and molds. Investigate the type and level of antibiotic resistance of microorganisms isolated in various infectious processes, including catheter-associated infections. To investigate the ability of the obtained clinical isolates of microorganisms to form a biofilm structure. Carry out screening and detailed study of antimicrobial activity of the obtained extracts with determination of the minimum inhibitory concentration of drugs. Conduct research to determine the rate of acquisition of resistance to these substances. Obtain clinical material from patients in intensive care units to isolate cultures of microorganisms of different groups - gram-positive and gram-negative bacteria, yeasts, as well as molds to form a museum of multidrug-resistant pathogens of nosocomial infectious diseases. Product Description popup.authors Konechnyi Yulian T Korniychuk Olena P Pavlyak Uliana V Panas Marta A Tymchuk Iryna V popup.nrat_date 2020-12-16 Close