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Information × Registration Number 0220U104550, 0120U103382 , R & D reports Title Design and study of physicochemical properties and bioactivity of self-assembling calixarene and dihydropyridine hybrids for DNA delivery popup.stage_title Head Rodik Roman V., Кандидат хімічних наук Registration Date 22-12-2020 Organization Institute of Organic Chemistry NAS of Ukraine popup.description2  A method of synthesis was developed and samples of new symmetric dihydropyridine derivatives of calixarenes were synthesized and transferred to project partners from the Latvian Institute of Organic Synthesis (Riga) for the synthesis of amphiphilic cationic calixes [4] arenes. The structure of synthesized calixarenes was studied by quantum chemical calculations and NMR spectroscopy. Works on synthesis and research of self-association of amphiphilic cationic calixarenes are performed. These types of compounds are promising for the study of structure-activity relationships in the binding and transport of DNA into living cells. Product Description popup.authors Yesipenko Olexandr A. Kalchenko Vitaly I. Rodik Roman V. Silenko Oleg M. Cherenok Sergiy O. popup.nrat_date 2020-12-22 Close