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Information × Registration Number 0221U000095, 0120U104249 , R & D reports Title Advanced SERS-based nanoplatform for efficient detection of biomolecules and pathogens popup.stage_title Head Dzhagan Volodymyr M., Доктор фізико-математичних наук Registration Date 02-01-2021 Organization VE Lashkarev Institute of Semiconductor Physics of the National Academy of Sciences of Ukraine popup.description2 In accordance with the tasks for 2020, listed in the Technical Task, obtained a series of samples of thin films of gold and silver of different thickness on substrates of silicon, glass, and polymer, by thermal spraying in a vacuum. The homogeneity of the surface morphology of the films and the absence of surface roughness with a value greater than the allowable (nanometer units) were established. The selection of biomolecules (antibodies and oligonucleotides), the most promising both in terms of their relevance for detection and the possibility of their successful functionalization on metal surfaces and obtaining an amplified Raman signal. The technology of surface functionalization of the obtained metal films by small linker molecules (ligands) and biomolecules has been worked out and their spectroscopic characterization by IR Fourier spectroscopy and Raman light scattering has been carried out. In addition to the planned results, a new method for the synthesis of colloidal gold nanoparticles, which will be used in the next phase of the project. Based on this result, materials were prepared for two applications for patents of Ukraine. Product Description popup.authors Isaeva Oksana F Borova Mariya M. Buziashvili Anastasia Yu. Hreshchuk Oleksandr M. Kapush Olha A. Mazur Nazar V. Pirko Yaroslav V. Plohovska Svitlana G. Yuhymchuk Volodymyr O popup.nrat_date 2021-01-02 Close