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Information × Registration Number 0221U100270, 0120U100746 , R & D reports Title Determination of the role of radiation and psychogenic factors, polymorphism of the monoamine oxidase-A (MAOA-uVNTR) gene promoter in the formation of aggressive symptom complex in children - residents of radioactively contaminated territories and displaced children from the area of armed conflict popup.stage_title Head Stepanova Eugenia I., Доктор медичних наукChumak Anatolii A., Доктор медичних наук Registration Date 04-01-2021 Organization State Institution "National Research Centre For Radiation Medicine of National Academy of Medical Sciences of Ukraine" popup.description2 Object of research: children - residents of radioactively contaminated areas. Purpose: To determine the psychological state of children - residents of radioactively contaminated areas and to conduct a comprehensive clinical and laboratory examination. Research methods: clinical, psychological, molecular genetic, statistical. Results and their novelty. Most children had chronic somatic pathology, the index of pathological lesions was 4.9. A number of functional changes in the digestive, cardiovascular and immune systems have been identified. Almost half of the children showed an increase in catalase activity and ceruloplasmin content. Unsatisfactory living conditions and low material level were more often determined in children of the main group. According to the educational level, the presence of bad habits, the use of different approaches to education, the use of corporal punishment of the child, the frequency of conflicts in the family, probable differences between the observation groups are not defined. Assessment of the psycho-emotional sphere by the test "non-existent animal" revealed in the vast majority of children a state of aggression, the symptom complex of exhaustion significantly prevailed in children of the main group. The Bass – Darki questionnaire revealed high scores on all eight scales. The highest values were noted on the scales of "resentment" and "guilt". The index of aggression was excessive in 51.11% of children in the main group and in 48.28% in the comparison group, the total indicators of the hostility index exceeded the norm in 55.56% and 75.86% of children, respectively. The overall indicator of sleep quality in children of the main group was lower than in children of the comparison group, the most pronounced was "daytime dysfunction". Molecular genetic studies have found that the predominant allelic variants are variants with 3 and 4 tandem repeats. Introduction: 1 article, 1 thesis. Field of application - radiation medicine, pediatrics. Product Description popup.authors Abramenko Iryna V Aliokhina Svitlana M. Bilous Nataliia I Vdovenko Vitaliy Yu. Grycenko Tetyana V. Zygalo Viktor M. Kolpakov Igor Ye. Leonovych Olena S. Poznysz Viktoriya A. Stepanova Eugenia I. Chumak Anatolii A popup.nrat_date 2021-01-04 Close