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Information × Registration Number 0221U100442, 0118U001713 , R & D reports Title To evaluate of risks of late oncological and somato-neurological effects from the treatment of thyroid cancer for the substantiation of clinical and methodological support of special therapy popup.stage_title Head Васильєв Л Я., Registration Date 05-01-2021 Organization State Organization "Grigoriev Institute for Medical Radiologiy of the National Academy of Medical Sciences of Ukraine" popup.description2 Оbject of study: refined estimates of the risk of developing long-term negative iatrogenic effects, depending on the scheme of treatment of the first tumor in thyroid cancer. The purpose of the study: is to provide a scientific justification for the program of accompanying therapy for the treatment of thyroid tumors to prevent the long-term negative effects of special treatment. Research methods: methods of nonparametric statistics, technology of Data Mining. Theoretical results: it was shown that the duration of suppressive hormone therapy (SHT) should not exceed 7 months: its prolongation does not reduce the incidence of oncological complications, but leads to an increase in cardiovascular and complications of the female reproductive system. Practical results: it was developed and patented technology for predicting the recurrence of thyroid cancer based on the use as markers of certain levels of TG, TSH and thyroxine and technology for their prevention based on corticosteroid therapy before each course of radioiodine therapy (RT). Novelty: for the first time a list of risk factors for the development of long-term oncological and somatoneurological consequences of thyroid cancer treatment was formed. Markers for predicting long-term negative consequences of special treatment have been identified. Technologies for predicting recurrence of thyroid cancer and prevention of recurrence of differentiated thyroid cancer have been developed. Implementation efficiency: allows to increase the 10-year survival rate of patients. Field of use: medicine, radiology.  Product Description popup.authors Danilchenko Iryna O. Zats Olha S Kulinich Halyna V. Lukhovytska Nataliia I. Myrna Olha M. Pidchenko Nataliya S. Riiako Viktoriia M Radzishevska Yevheniia B Savchenko Antonina S. Solodovnikova Olena O. popup.nrat_date 2021-01-05 Close