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Registration Number

0221U102013, 0118U001126 , R & D reports

Title

Development of means of neurophysiological diagnostics and correction of the consequences of brain injury, contusion and post-traumatic stress disorder in ATO participants.

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Head

Makarchuk Mykola Yu., Доктор біологічних наук

Registration Date

27-01-2021

Organization

Taras Shevchenko National University of Kyiv

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The object of study - the physiological mechanisms of the brain and visceral systems of the body. The aim of the work is to develop an effective system for diagnosing neurophysiological and cognitive disorders in anti-terrorist operation soldiers based on elucidation of neurophysiological mechanisms of basic brain functions under conditions of brain damage, contusions and development of excessive psychoemotional stress, maladaptation syndromes, as well as development of new experimentally justified procedures, techniques and tools. Research methods - registration of EEG and ECG, author's computerized methods of testing the state of basic psychophysiological functions of man. The sexual features in the organization of structures of a brain at cognitive loading which need to be considered at diagnosis of defeats of a brain are revealed. The study identified key neuromarkers in the differential diagnosis of post-traumatic stress disorder (PTSD) and closed traumatic brain injury (TBI). An application for a patent for the invention № 202001353 "Method of differential diagnosis of closed trauma and PTSD" from 28.02.2020, It was found that the background EEG of patients with closed traumatic brain injury and contusion have the same EEG signs of concussion, and differ only in different complaints, except for headache. Detracted fluctuation analysis (DFA) proved to be an effective method of assessing the functional state of the brain, demonstrated the ability to determine long-term and short-term relationships in EEG time series. 

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Berezovchuk Ludmyla V
Zyma Igor H.
Koval Tetyana V.
Torgalo Elizaveta О.
Filimonova Natalya B.

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2021-01-27