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Information × Registration Number 0221U102292, 0119U000091 , R & D reports Title Develop biotechnological approaches for the production of a vaccine against infectious diseases of animals caused by C. perfringens and E. coli popup.stage_title Head Zhovnir Oleksandr M, Registration Date 29-01-2021 Organization THE INSTITUTE OF VETERINARI MEDICINE OF THE NATIONAL ACADEMY OF AGRARIAN SCIENCES OF UKRAINE popup.description2 Bacteriological monitoring of bacterial diseases of pigs on the territory of Ukraine for 2011-2019 and found that the most common colibacillosis, swine edema, erysipelas, salmonellosis, anaerobic enterotoxemia, and anaerobic dysentery. Indication and identification of pathogens from the sent biological material is carried out and their cultural and morphological features are studied; selection of promising strains of C. perfringens types A, B, C and D, and E. coli the adhesive properties of E. coli in RA formulations with complex anti-adhesive serum were studied; the modes of cultivation, inactivation, sorption of antigens are worked out; making experimental samples of the associated vaccine; laboratory control of quality and safety of the made experimental samples of vaccines is carried out; the effectiveness of the vaccine on laboratory and farm animals was studied. Developed and approved "Technological regulations for the manufacture and control of vaccines" Perfricol "associated inactivated concentrated against perfringiosis and Escherichia coli animals." Methodical recommendations for bacteriological monitoring and laboratory diagnosis of infectious (anaerobic) enterotoxemia of animals have been developed. Product Description popup.authors popup.nrat_date 2021-01-29 Close