Search academic texts

Information × Registration Number 0221U102921, 0120U104348 , R & D reports Title Improvement of therapeutic diagnostic technologies and biosecurity measures of mono - and mixed tick - borne infection. popup.stage_title Head Andreychyn Mykhailo A., Доктор медичних наук Registration Date 11-02-2021 Organization I. Horbachevsky Ternopil State Medical University popup.description2  GDR report (intermediate): 45 pages, 17 figures, 9 tables, 33 sources. LYME-BORELIOSIS, B. BURGDORFERI SL (B. BURGDORFERI SS, B. AFZELIІ AND B. GARINII, B. SPIELMANII), B MIYAMOTOI, A. PHAGOCYTOPHILUM, BABESIA SPP, LYMIC BORHIRIITIS TICKS, THERMOGRAPHY, POLYMERASE CHAIN ??REACTION Object of research: Ixodes mites, selected from patients and from the environment of 5 parks of Ternopil; patients with erythematous and erythematous forms of Lyme borreliosis; persons attacked by ticks infected with A. phagocytophilum; pregnant women with pathology of pregnancy. Purpose: to establish the frequency of natural infestation of mites B. burgdorferi sensu lato, A. Phagocytophilum, B. miyamotoi and Babesia spp., Selected from humans and the environment of 5 parks in Ternopil; apply the method of immunoblot EUROLINE Borrelia RN-AT adv to establish the involvement of pathogens B. burgdorferi s.l. (B. burgdorferi s.s., B. garinii, B. afzelii, B. spielmanii) to clinical manifestations of acute LB (migrating erythema and Lyme arthritis); apply real-time PCR to diagnose tick-borne infections in pregnant women with a burdensome obstetric history; use the method of remote thermometry to diagnose subclinical cutaneous form of LB. Research methods: clinical (physical, questionnaire); epidemiological; laboratory (PCR: DNA of the main species of Borrelia burgdorferi, Borrelia miamotoi, Anaplasma phagocytophilum, RNA of Babesia sp. in the material from patients and ticks; ELISA: IgM and IgG antibodies to the main species of Borrelia burgdorferi in the serum of patients: immunobloc B. burgdorferi (B. burgdorferi sl, B. garinii, B. afzelii, B. spielmanii) in the serum of patients); remote thermometry method; statistical. In the identification of mites selected from humans in 2020, ticks of the same species ? I. ricinus were detected, dominated by adults (50.7%). Product Description popup.authors popup.nrat_date 2021-02-11 Close