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Information × Registration Number 0221U103282, 0116U000253 , R & D reports Title To study the mechanisms of formation natural immunoresistance and antioxidant protection in metabolic diseases of farm animals with high genetic potential productivity popup.stage_title Head Kovalenko Larysa V., Кандидат біологічних наук Registration Date 17-02-2021 Organization National Scientific Center Institute of Experimental and Clinical Medicine popup.description2 The aim of the work is to establish the influence of metabolic disorders on the state of indicators of natural immunoresistance and compensatory-adaptive reactions in the body of farm animals and poultry. Research methods - biochemical, histomorphological. The dynamics of changes in markers of the immune response (total protein, circulating immune complexes, seromucoids, lysozyme activity, nitric oxide) in vitamin A and E-deficiency and revealed signs of immunosuppressive status in animals and poultry, including signs of suppression of cellular immunity in domestic birds with vitamin deficiencies. It is proved that the decrease in the supply of animals with macro-and microelements is accompanied by a decrease in the total protein content and activity of lysozyme and catalase, as well as the activation of lipid peroxidation processes. In violation of lipid metabolism (increased levels of total lipids, triglycerides and total cholesterol) in the serum of cows found an increase in total protein and its fractions, as well as activation of lipid peroxidation. The generalized results are summarized in 4 analytical reports and methodical recommendations "Methodical bases of diagnostics of metabolic disorders in cattle with high genetic potential of productivity" are developed.   Product Description popup.authors Boiko Viktoria S Muzyka Denys V. Orobchenko Oleksandr L. Rudenko Olena P popup.nrat_date 2021-02-17 Close